Four years ago, when AMiCI was established, there was clear evidence that antimicrobial resistance (AMR) had emerged as a global health risk. While effective and prudent stewardship of antimicrobial products were being promoted as necessary for management and potential mitigation of this risk, there was increasing recognition of the possibilities that antimicrobial coatings (AMCs) presented. AMCs and some associated technologies were not necessarily new. For
A variety of bacteria such as Staphylococcus aureus and Staphylococcus epidermidis can survive in host cell, even in phagocystes (e.g. macrophages) after phagocytosis, causing intracellular infections. Treatment of this intracellular infections often fails due to the low intracellular efficacy of most conventional antimicrobials such as antibiotics. Thus, novel techniques that can improve intracellular efficacy of antibiotics are highly needed. Poster presented by Xiaolin Zhang during
THE POLY-PREVENTT project poster presented during the AMiCI Workshop for Early Career Investigators (ECIs) and Short Term Scientific Missions (STSM). Riga, Latvia, 7th of March 2019 by Suzana Lopez.
In this work, two antifouling polymer brushes were tested at different shear stress conditions to evaluate their performance in reducing the initial adhesion of Escherichia coli. Assays were performed using a parallel plate flow chamber and a shear stress range between 0.005 and 0.056 Pa, previously determined by numerical simulation. These shear stress valuesare found in different locations in the human body where biomedical devices
Papadopoulos Panagiotis 2019 Chitosan is a natural, nontoxic, biodegradable biopolymer which derives by the deacetylation of chitin, a main component of the shells of crustaceans such shrimp, crab and crawfish. Chitosan as well as it’s oligomers, receive considerable attention due to their antimicrobial, antitumor and hypocholesterolemic abilities. Chitosan based edible coating and films, incorporated or not with other antimicrobial agents (essential oils, lauric alginate, ester,
We focus on the fate and effects of metals from anthropogenic sources; applying life cycle assessment (LCA) approach to characterize and evaluate the potential environmental impacts of metal-specific emissions. Advance the quantification methods to assess metal toxicity to be able to explain different environmental impact profiles in the frame of LCA studies, and establish clear guidelines to account for emissions in the inventory evaluation of
Collagen is a polymer that naturally occurs in the human body, and due to its characteristic properties such as biocompatibility, and nontoxicity is commonly used in the biomedical and cosmetic field. Thymol is a monoterpene phenol which shows many biological activities, such as antimicrobial, antioxidant, anti-inflammatory and local antiseptic . Prepared collagen/thymol material showed antibacterial properties . In this study, surface properties of this material
Biofilms are problematic in the health sector since they are responsible for 65% of the hospital acquired infections associated with medical devices. Hydrodynamics have a very strong influence in the process of biofilm formation.Flow behavior in 96-well microtiter plates (MTPs) was simulated for shaking frequencies between 50 and 200 rpm and diameters from 25 to 100 mm. Shear strain values up to 150s-1 were obtained.
Within the field of urogynecology there is an urge to develop an optimal biocompatible implant for the improvement of surgical repair of pelvic organs prolapse. Bacterial contamination of the implant seems unavoidable during surgery. Even after infection prophylaxes, the vagina is colonized with different bacterial species, with Staphylococcus aureus being one of the most common. Subclinical contamination of the implant is important since complications are
The objectives: the fabrication of phytochemical based antimicrobial nanofiber composites via electrospinning Polylactic acid (PLA) used for the nanofiber fabrication. Tannic acid used as antimicrobial agent. The antimicrobial activity of the composites assessed against Escherichia coli. Poster presented during the AMiCI Workshop for Early Career Investigators (ECIs) and Short Term Scientific Missions (STSM). Riga, Latvia, 7th of March 2019